Revised computational metagenomic processing uncovers hidden and biologically meaningful functional variation in the human microbiome

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Revised computational metagenomic processing uncovers hidden and biologically meaningful functional variation in the human microbiome

BACKGROUND Recent metagenomic analyses of the human gut microbiome identified striking variability in its taxonomic composition across individuals. Notably, however, these studies often reported marked functional uniformity, with relatively little variation in the microbiome's gene composition or in its overall metabolic capacity. RESULTS Here, we address this surprising discrepancy between t...

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ژورنال

عنوان ژورنال: Microbiome

سال: 2017

ISSN: 2049-2618

DOI: 10.1186/s40168-017-0231-4